BDBM50314075 1-(5-(2-(6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-ylamino)ethyl)thiazol-2-yl)-3-(5-methyl-2-(trifluoromethyl)furan-3-yl)urea::1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea::CHEMBL1092830

SMILES Cc1cc(NC(=O)Nc2ncc(CCNc3cc(Nc4nnc[nH]4)ncn3)s2)c(o1)C(F)(F)F

InChI Key InChIKey=KNTGXMNWVXZIMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314075   

TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314075(1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)...)
Affinity DataIC50: 720nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed