BDBM50313784 (R)-9-(((2-(benzofuran-2-yl)-2-hydroxyethyl)(methyl)amino)methyl)-N-(4-chlorobenzyl)-1-methyl-2,7-dioxo-1,2,3,7-tetrahydropyrido[1,2,3-de]quinoxaline-6-carboxamide::CHEMBL1077295

SMILES CN(C[C@@H](O)c1cc2ccccc2o1)Cc1cc2N(C)C(=O)Cn3cc(C(=O)NCc4ccc(Cl)cc4)c(=O)c(c1)c23

InChI Key InChIKey=MYJRZQIQQWFCKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313784   

TargetDNA polymerase alpha catalytic subunit(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313784((R)-9-(((2-(benzofuran-2-yl)-2-hydroxyethyl)(methy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant DNA polymerase alpha expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed