BDBM50313696 CHEMBL1086427::N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)butyramide

SMILES CCCC(=O)Nc1n[nH]c2c(F)c(Cl)c(cc12)-c1ccccc1

InChI Key InChIKey=PREQLWGLUIHGJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313696   

TargetCyclin-dependent kinase 1(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)buty...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)buty...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMicrotubule-associated protein tau(Rat)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)buty...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Tau phosphorylation in rat cerebral cortex after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)buty...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed