BDBM50313618 1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazolidin-2-one::CHEMBL1085672

SMILES Clc1cccc(c1)N1CCN(CC2CCCCN2)C1=O

InChI Key InChIKey=HVSRNYNPOUFDNJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313618   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataIC50: 7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataKi:  2.00E+3nMAssay Description:Activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed