BDBM50313553 CHEMBL1099373::CHEMBL1204415::{3-[1-(2,6-Difluoro-phenyl)-6-fluoro-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine

SMILES CNCCCC1Cc2cc(F)ccc2N(c2c(F)cccc2F)S1(=O)=O

InChI Key InChIKey=KPUDPAXPYHVNAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313553   

LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 25nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 27nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 600nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed