BDBM50313552 CHEMBL1096001::CHEMBL1204414::{3-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine

SMILES CNCCCC1Cc2cc(F)ccc2N(c2ccccc2F)S1(=O)=O

InChI Key InChIKey=CLLQMGVKRYVVFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313552   

LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed