BDBM50313548 CHEMBL1077209::CHEMBL1204410::[3-(2,2-Dioxo-1-phenyl-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl)-propyl]-methyl-amine

SMILES CNCCCC1Cc2ccccc2N(c2ccccc2)S1(=O)=O

InChI Key InChIKey=OYUQXAOEDHJVKK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50313548   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 88nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 12nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed