BDBM50313470 4-propyl-6-m-tolylpyrimidine-2-carbonitrile::CHEMBL1082859

SMILES CCCc1cc(nc(n1)C#N)-c1cccc(C)c1

InChI Key InChIKey=LWTLVKKUNGVFHE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313470   

TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 181nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313470(4-propyl-6-m-tolylpyrimidine-2-carbonitrile | CHEM...)
Affinity DataIC50: 182nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed