BDBM50313468 4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbonitrile::CHEMBL1082857

SMILES CCCc1cc(nc(n1)C#N)-c1cccc(c1)C1CCCC1

InChI Key InChIKey=ASFRYMKNZGDSTP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313468   

TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 457nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin S(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 457nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313468(4-(3-cyclopentylphenyl)-6-propylpyrimidine-2-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed