BDBM50313446 CHEMBL1096003::N-(((2R,4aS,5R,10bS)-9-chloro-7-fluoro-5-phenyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methyl)-2-(dimethylamino)ethanesulfonamide

SMILES CN(C)CCS(=O)(=O)NC[C@H]1CC[C@H]2[C@@H](Nc3c(F)cc(Cl)cc3[C@H]2O1)c1ccccc1

InChI Key InChIKey=XNXPMZDKAOHHSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313446   

TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313446(N-(((2R,4aS,5R,10bS)-9-chloro-7-fluoro-5-phenyl-3,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed