BDBM50313433 CHEMBL1084431::N-(2-aminoethyl)-4-methyl-N-(((2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methyl)benzamide

SMILES Cc1ccc(cc1)C(=O)N(CCN)C[C@H]1CC[C@H]2[C@@H](Nc3ccc(cc3[C@H]2O1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=RAQSTOCPDXWQMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313433   

TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313433(N-(2-aminoethyl)-4-methyl-N-(((2R,4aS,5R,10bS)-5-p...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed