BDBM50313416 (4aS,5R,10bS)-9-tert-butyl-5-(3-fluorophenyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline::CHEMBL1077357

SMILES CC(C)(C)c1ccc2N[C@H]([C@@H]3CCCO[C@@H]3c2c1)c1cccc(F)c1

InChI Key InChIKey=TUTZJRZGILWWMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313416   

TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313416((4aS,5R,10bS)-9-tert-butyl-5-(3-fluorophenyl)-3,4,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313416((4aS,5R,10bS)-9-tert-butyl-5-(3-fluorophenyl)-3,4,...)
Affinity DataIC50: 870nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed