BDBM50313376 (6S,7R,8R,9S)-6-(3-(4-ethylbenzyl)-4-methylphenyl)-5-oxa-2-azaspiro[3.5]nonane-7,8,9-triol::CHEMBL1091809

SMILES CCc1ccc(Cc2cc(ccc2C)[C@@H]2OC3(CNC3)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=LOLWWXQQRJQJES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313376   

TargetSodium/glucose cotransporter 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313376((6S,7R,8R,9S)-6-(3-(4-ethylbenzyl)-4-methylphenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313376((6S,7R,8R,9S)-6-(3-(4-ethylbenzyl)-4-methylphenyl)...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed