BDBM50313372 (3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)-2,2-bis(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1094713

SMILES COc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(CO)(CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=VDTAFRVZXXUACU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313372   

TargetSodium/glucose cotransporter 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313372((3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)pheny...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313372((3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)pheny...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed