BDBM50313366 (2R,3S,4R,6R)-6-(3-(4-ethylbenzyl)-4-methylphenyl)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol::CHEMBL1085189

SMILES CCc1ccc(Cc2cc(ccc2C)[C@H]2C[C@@H](O)[C@H](O)[C@@H](CO)O2)cc1

InChI Key InChIKey=PDKMPBWKXXEKCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313366   

TargetSodium/glucose cotransporter 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313366((2R,3S,4R,6R)-6-(3-(4-ethylbenzyl)-4-methylphenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50313366((2R,3S,4R,6R)-6-(3-(4-ethylbenzyl)-4-methylphenyl)...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50313366((2R,3S,4R,6R)-6-(3-(4-ethylbenzyl)-4-methylphenyl)...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed