BDBM50313299 (1S,5R)-8-(4-tert-butylphenylsulfonyl)-1-methyl-8-azabicyclo[3.2.1]octane-3,3-diol::CHEMBL1080158

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@@H]2CC[C@@]1(C)CC(O)(O)C2

InChI Key InChIKey=NMFVUIZOWMLQAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313299   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313299((1S,5R)-8-(4-tert-butylphenylsulfonyl)-1-methyl-8-...)
Affinity DataIC50: 740nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313299((1S,5R)-8-(4-tert-butylphenylsulfonyl)-1-methyl-8-...)
Affinity DataIC50: 114nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed