BDBM50313133 3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-3-yl)-1H-indole::CHEMBL1081110

SMILES COc1ccc2n(cc(c2c1)S(=O)(=O)c1cccc(F)c1)C1CCCNC1

InChI Key InChIKey=NFVSQUPZIYCBJF-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313133   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313133(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313133(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-...)
Affinity DataKi:  10.7nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed