BDBM50313115 CHEMBL1081037::N-cyclopropyl-3-(1-(2,4-difluorophenyl)-7-methyl-1H-pyrazolo[4,3-d]pyridazin-4-yloxy)-4-methylbenzamide

SMILES Cc1ccc(cc1Oc1nnc(C)c2n(ncc12)-c1ccc(F)cc1F)C(=O)NC1CC1

InChI Key InChIKey=KYFXLPVTHUBQLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313115   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50313115(N-cyclopropyl-3-(1-(2,4-difluorophenyl)-7-methyl-1...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed