BDBM50313110 4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-methyl-1H-pyrazolo[4,3-d]pyridazin-4-ylamino)benzamide::CHEMBL1076560

SMILES Cc1nnc(Nc2cc(ccc2Cl)C(=O)NC2CC2)c2cnn(-c3ccc(F)cc3)c12

InChI Key InChIKey=LWHJTUCBJQXLDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313110   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50313110(4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed