BDBM50313109 CHEMBL1082182::N-cyclopropyl-3-(1-(4-fluorophenyl)-7-methyl-1H-pyrazolo[4,3-d]pyridazin-4-ylamino)-4-methylbenzamide

SMILES Cc1ccc(cc1Nc1nnc(C)c2n(ncc12)-c1ccc(F)cc1)C(=O)NC1CC1

InChI Key InChIKey=GRFHDHQWGQYHJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313109   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50313109(N-cyclopropyl-3-(1-(4-fluorophenyl)-7-methyl-1H-py...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed