BDBM50313104 4-chloro-N-cyclopropyl-3-(1-(2,4-difluorophenyl)-1H-pyrazolo[4,3-d]pyridazin-4-yloxy)benzamide::CHEMBL1088167

SMILES Fc1ccc(c(F)c1)-n1ncc2c(Oc3cc(ccc3Cl)C(=O)NC3CC3)nncc12

InChI Key InChIKey=RYZANMAYZILVNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313104   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50313104(4-chloro-N-cyclopropyl-3-(1-(2,4-difluorophenyl)-1...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed