BDBM50313102 4-chloro-N-cyclopropyl-3-(1-(2,4-difluorophenyl)-1H-pyrazolo[4,3-d]pyridazin-4-ylamino)benzamide::CHEMBL1088032

SMILES Fc1ccc(c(F)c1)-n1ncc2c(Nc3cc(ccc3Cl)C(=O)NC3CC3)nncc12

InChI Key InChIKey=IOUDTDNDODCACW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313102   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50313102(4-chloro-N-cyclopropyl-3-(1-(2,4-difluorophenyl)-1...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed