BDBM50313078 5-(furan-2-yl)-6-(pyrimidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one::CHEMBL1076563

SMILES O=c1[nH]c2cc(-c3ccncn3)c(nc2[nH]1)-c1ccco1

InChI Key InChIKey=MKVQVZUHJKLKRR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313078   

TargetAdenosine receptor A2b(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50313078(5-(furan-2-yl)-6-(pyrimidin-4-yl)-1H-imidazo[4,5-b...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50313078(5-(furan-2-yl)-6-(pyrimidin-4-yl)-1H-imidazo[4,5-b...)
Affinity DataKi:  317nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50313078(5-(furan-2-yl)-6-(pyrimidin-4-yl)-1H-imidazo[4,5-b...)
Affinity DataKi:  769nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed