BDBM50312999 (S)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione::CHEMBL1081972

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cccc(C[C@H](O)CO)c2)c2ccccc12

InChI Key InChIKey=IVLXFYOVQYKSNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312999   

TargetProtein kinase C alpha type(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312999((S)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(1-methyl-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312999((S)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(1-methyl-...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed