BDBM50312938 (S)-7-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)propylamino)thiazol-5-yl)phthalazin-1(2H)-one::CHEMBL1082030

SMILES N[C@H](CNc1ncc(s1)-c1ccc2cn[nH]c(=O)c2c1)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IJVKFTRBSAEFTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312938   

LigandPNGBDBM50312938((S)-7-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312938((S)-7-(2-(2-amino-3-(4-(trifluoromethyl)phenyl)pro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed