BDBM50312876 4-(4-(2-fluorophenyl)thiazol-2-ylamino)phenol::CHEMBL1081276::N-aryl-4-aryl-1,3-thiazole-2-amine, 7

SMILES Oc1ccc(Nc2nc(cs2)-c2ccccc2F)cc1

InChI Key InChIKey=JGPHUSPVLXVWPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312876   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Korea Research Institute of Chemical Technology

LigandPNGBDBM50312876(N-aryl-4-aryl-1,3-thiazole-2-amine, 7 | CHEMBL1081...)
Affinity DataIC50: 81nMpH: 7.4 T: 2°CAssay Description:5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2012
Entry Details Article
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50312876(N-aryl-4-aryl-1,3-thiazole-2-amine, 7 | CHEMBL1081...)
Affinity DataIC50: 360nMAssay Description:Inhibition of VCP assessed as conversion of ATP to ADP by enzyme coupled glucokinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed