BDBM50312840 CHEMBL1076680::US9139546, 16::[11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(thiophen-2-yl)methanol

SMILES COc1cc(cc(OC)c1-c1cc(Cl)cc(Cl)c1)C(O)c1cccs1

InChI Key InChIKey=ABSMJNBBBBHGTP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312840   

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi:  0.270nM ΔG°:  -13.3kcal/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Rat)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to rat brain CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.32kcal/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50312840([11C](3',5'-dichloro-2,6-dimethoxybiphenyl-4-yl)(t...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed