BDBM50312716 (S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-(trifluoromethyl)phenyl)methyl)-6',8'-dihydro-5'H-spiro[cyclobutane-1,7'-quinolin]-5'-ol::CHEMBL1081802

SMILES O[C@H]1CC2(CCC2)Cc2nc(C3CCCC3)c([C@@H](F)c3ccc(cc3)C(F)(F)F)c(C3CCCCC3)c12

InChI Key InChIKey=KVTOMNNOROBXFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312716   

TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed