BDBM50312713 (S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)phenyl)methyl)-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol::CHEMBL1081287

SMILES CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=LKISIMKAWPWFFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312713   

TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed