BDBM50312709 CHEMBL1080749::trans-4-cyclohexyl-3-(hydroxy(4-(trifluoromethyl)phenyl)methyl)-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol

SMILES CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IDGSHGWPUQMIEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312709   

TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312709(trans-4-cyclohexyl-3-(hydroxy(4-(trifluoromethyl)p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed