BDBM50312677 CHEMBL1076673::Podophyllotoxinyl 4-[4-{5-(dimethylamino)naphthalene-1-sulfonamido}benzylamino]-4-oxobutanoate

SMILES COc1cc(cc(OC)c1OC)[C@@H]1[C@H]2[C@@H](COC2=O)[C@H](OC(=O)CCC(=O)NCc2ccc(NS(=O)(=O)c3cccc4c(cccc34)N(C)C)cc2)c2cc3OCOc3cc12

InChI Key InChIKey=MRGXTHHOSIIBES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312677   

TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50312677(Podophyllotoxinyl 4-[4-{5-(dimethylamino)naphthale...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50312677(Podophyllotoxinyl 4-[4-{5-(dimethylamino)naphthale...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed