BDBM50312650 5,4'-dihydroxyflavone::5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL484662

SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1

InChI Key InChIKey=STYVAERQLVJTRI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312650   

TargetSialidase-2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50312650(5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Meijo University

Curated by ChEMBL
LigandPNGBDBM50312650(5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5...)
Affinity DataIC50: 851nMAssay Description:Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Meijo University

Curated by ChEMBL
LigandPNGBDBM50312650(5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5...)
Affinity DataIC50: 860nMAssay Description:Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50312650(5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 5...)
Affinity DataKi:  1.03E+5nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed