BDBM50312619 (4-(6-((4-(Methylsulfonyl)piperazin-1-yl)methyl)-2-phenylthieno-[3,2-d]pyrimidin-4-yl)morpholine::CHEMBL1085159

SMILES CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2ccccc2)CC1

InChI Key InChIKey=SQTKRVQOAMDAGJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312619   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50312619((4-(6-((4-(Methylsulfonyl)piperazin-1-yl)methyl)-2...)Copy SMILESCopy InChI

Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as PIP3 product formation by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2010
Entry Details Article
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