BDBM50312617 1-(2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)ethanol::CHEMBL1083507

SMILES CC(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cccc2[nH]ncc12

InChI Key InChIKey=VIOPFQOZMDFRIZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312617   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50312617(1-(2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]py...)Copy SMILESCopy InChI

Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as PIP3 product formation by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2010
Entry Details Article
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