BDBM50312616 2-[2-(2-Amino-4-methyl-pyrimidin-5-yl)-4-morpholin-4-yl-thieno-[3,2-d]pyrimidin-6-yl]-propan-2-ol::CHEMBL1086403

SMILES CC(=O)NCc1cc2nc(nc(N3CCOCC3)c2s1)-c1cccc2[nH]ncc12

InChI Key InChIKey=JSRNAKDXAPQVRG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312616   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50312616(2-[2-(2-Amino-4-methyl-pyrimidin-5-yl)-4-morpholin...)Copy SMILESCopy InChI

Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as PIP3 product formation by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/17/2010
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL