BDBM50312595 CHEMBL1089718::N-Butyl-4-[(2,4-dichlorophenyl)(phenyl)methyl]piperazine-1-carboxamide

SMILES CCCCNC(=O)N1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=KBCABXWNLQBGLN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312595   

TargetCannabinoid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312595(N-Butyl-4-[(2,4-dichlorophenyl)(phenyl)methyl]pipe...)
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP-55940-induced Ca2+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312595(N-Butyl-4-[(2,4-dichlorophenyl)(phenyl)methyl]pipe...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312595(N-Butyl-4-[(2,4-dichlorophenyl)(phenyl)methyl]pipe...)
Affinity DataKi:  918nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed