BDBM50312593 1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidin-1-ylcarbonyl)piperazine::CHEMBL1089716

SMILES Clc1ccc(C(N2CCN(CC2)C(=O)N2CCCCC2)c2ccccc2)c(Cl)c1

InChI Key InChIKey=BHUFAMDEGOUAKE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312593   

TargetCannabinoid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312593(1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP-55940-induced Ca2+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312593(1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312593(1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...)
Affinity DataKi:  987nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed