BDBM50312571 6-(2,4-Dihydroxyphenyl)-4-methyl-2-(3-methyl-5-oxo-4-(thiophen-2-ylmethylene)-4,5-dihydro-1H-pyrazol-1-yl)-N-(3-nitrophenyl)-1,6-dihydropyrimidine-5-carboxamide::CHEMBL1087566

SMILES Cc1nn(c([O-])c1[CH+]c1cccs1)C1=NC(C(C(=O)Nc2cccc(c2)[N+]([O-])=O)=C(C)N1)c1ccc(O)cc1O

InChI Key InChIKey=ZXXDBMCSQISGEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312571   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312571(6-(2,4-Dihydroxyphenyl)-4-methyl-2-(3-methyl-5-oxo...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312571(6-(2,4-Dihydroxyphenyl)-4-methyl-2-(3-methyl-5-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed