BDBM50312566 2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methyl-N-(3-nitrophenyl)pyrimidine-5-carboxamide::CHEMBL1083509

SMILES Cc1nc(nc(-c2ccc(O)cc2O)c1C(=O)Nc1cccc(c1)[N+]([O-])=O)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=SGBCBBPNEGMTLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312566   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312566(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312566(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed