BDBM50312561 2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)-l,6-dihydropyrimidine-5-carboxamide::CHEMBL1086151

SMILES CC1=NC(Nc2ccc(cc2Cl)[N+]([O-])=O)=NC(C1C(=O)Nc1cccc(c1)[N+]([O-])=O)c1ccc(O)cc1O

InChI Key InChIKey=ZBTFWTRHMFXNCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312561   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312561(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312561(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed