BDBM50312525 (2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol::1-deoxy-L-idonojirimycin::CHEMBL175901::L-ido-1-Deoxynojirimycin

SMILES OC[C@@H]1NC[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=LXBIFEVIBLOUGU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50312525   

TargetSucrase-isomaltase, intestinal(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGlycogen debranching enzyme(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of rat intestinal sucrase using p-nitrophenyl glycoside as substrate assessed as release of p-nitrophenol measured by spectrometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of rat intestinal isomaltase using p-nitrophenyl glycoside as substrate assessed as release of p-nitrophenol measured by spectrometric ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed