BDBM50312083 3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-1-carboxylate::CHEMBL1081019

SMILES Clc1cccc(OC(=O)N2CCN(CC2)c2ncccc2Cl)c1

InChI Key InChIKey=VGCOQJLQONFPQX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312083   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 910nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed