BDBM50312002 (S)-hexyl 5-(2-(1-benzylpiperidin-4-yl)ethylamino)-5-oxo-2-(thieno[2,3-b]thiophene-2-carboxamido)pentanoate::CHEMBL1080274

SMILES CCCCCCOC(=O)[C@H](CCC(=O)NCCC1CCN(Cc2ccccc2)CC1)NC(=O)c1cc2ccsc2s1

InChI Key InChIKey=ONGQTEYIIKGJGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312002   

TargetAcetylcholinesterase(Bovine)
Instituto De Quimica Medica (Csic)

Curated by ChEMBL
LigandPNGBDBM50312002((S)-hexyl 5-(2-(1-benzylpiperidin-4-yl)ethylamino)...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of AChE in bovine erythrocyte by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Instituto De Quimica Medica (Csic)

Curated by ChEMBL
LigandPNGBDBM50312002((S)-hexyl 5-(2-(1-benzylpiperidin-4-yl)ethylamino)...)
Affinity DataIC50: 700nMAssay Description:Inhibition of BuChE in horse serum by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Instituto De Quimica Medica (Csic)

Curated by ChEMBL
LigandPNGBDBM50312002((S)-hexyl 5-(2-(1-benzylpiperidin-4-yl)ethylamino)...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human AChE in erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Instituto De Quimica Medica (Csic)

Curated by ChEMBL
LigandPNGBDBM50312002((S)-hexyl 5-(2-(1-benzylpiperidin-4-yl)ethylamino)...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human BuChE in serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed