BDBM50311807 (1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)phenyl)-N-cyclopropyl-N-(3-methoxy-2-methylbenzyl)-9-azabicyclo[3.3.1]non-2-ene-2-carboxamide::CHEMBL1076454

SMILES COc1cccc(CN(C2CC2)C(=O)C2=C(C[C@H]3CCC[C@H]2N3)c2ccc(CCCOc3c(F)ccc(F)c3Cl)cc2)c1C

InChI Key InChIKey=VUZIYEFWZVSMGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311807   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311807((1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)prop...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of human rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311807((1R,5R)-3-(4-(3-(2-chloro-3,6-difluorophenoxy)prop...)
Affinity DataIC50: 101nMAssay Description:Inhibition of human rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed