BDBM50311804 (1S,5S)-7-{4-[3-(2-Chloro-3,6-difluoro-phenoxy)-propyl]-phenyl}-3,3-dioxo-3lambda*6*-thia-9-aza-bicyclo[33.1]non-6-ene-6-carboxylic acid cyclopropyl-(2,3-dichloro-benzyl)-amide::CHEMBL1076445

SMILES Fc1ccc(F)c(OCCCc2ccc(cc2)C2=C([C@H]3CS(=O)(=O)C[C@H](C2)N3)C(=O)N(Cc2cccc(Cl)c2Cl)C2CC2)c1Cl

InChI Key InChIKey=ULNCEZPLMLOWSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311804   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311804((1S,5S)-7-{4-[3-(2-Chloro-3,6-difluoro-phenoxy)-pr...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed