BDBM50311798 4-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)phenyl)-N-cyclopropyl-N-(2,3-dichlorobenzyl)-1,2,5,6-tetrahydropyridine-3-carboxamide::CHEMBL1088290

SMILES Fc1ccc(F)c(OCCCc2ccc(cc2)C2=C(CNCC2)C(=O)N(Cc2cccc(Cl)c2Cl)C2CC2)c1Cl

InChI Key InChIKey=LEPZPTOEMLDSMH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311798   

TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311798(4-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)pheny...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human rennin in human plasma assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRenin(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311798(4-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)pheny...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311798(4-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)pheny...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed