BDBM50311791 4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)biphenyl-4-carboxylic acid::CHEMBL1080469

SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=RQQDYLFGRBOAIF-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311791   

TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311791(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at PPARdelta co-transfected with GAL4-PPAR fusion protein assessed as inhibition of GW-501516-induced response by luciferase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311791(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at PPARdelta receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311791(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  170nMAssay Description:Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells co-transfected with Gal4 assessed as beta-galactosidase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311791(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  170nMAssay Description:Partial agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed