BDBM50311788 4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)-2-methylbiphenyl-3-carboxylic acid::CHEMBL1081354

SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C

InChI Key InChIKey=ZQMRWLOZDCPEGS-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311788   

TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311788(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at PPARalpha receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311788(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at PPARdelta receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311788(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  1.60nMAssay Description:Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells co-transfected with Gal4 assessed as beta-galactosidase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311788(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50311788(4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...)
Affinity DataEC50:  1.60nMAssay Description:Partial agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed