BDBM50311688 CHEMBL1080460::N-(2-methoxybenzyl)-1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide

SMILES CNCCNCc1cccc(c1)-n1nc(cc1C(=O)NCc1ccccc1OC)C(F)(F)F

InChI Key InChIKey=CYIZQJGLXPBOFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311688   

LigandPNGBDBM50311688(N-(2-methoxybenzyl)-1-(3-((2-(methylamino)ethylami...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PRMT1 expressed in Escherichia coli by microbeta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50311688(N-(2-methoxybenzyl)-1-(3-((2-(methylamino)ethylami...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged human recombinant SET7/9 expressed in Escherichia coli by microbeta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Mouse)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50311688(N-(2-methoxybenzyl)-1-(3-((2-(methylamino)ethylami...)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant CARM1 expressed in Sf9 cells by microbeta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed