BDBM50311677 (4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3,4,4a,5,6,10b,11,12,12a-decahydrochrysen-1(4bH)-one::CHEMBL1076306

SMILES COc1cc2[C@H]3CC[C@@]4(C)[C@@H](CCCC4=O)[C@@H]3CCc2cc1O

InChI Key InChIKey=FBBUVYMNJTXJOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311677   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50: 85nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institute of Experimental Genetics

Curated by ChEMBL
LigandPNGBDBM50311677((4bR,10bS,12aS)-8-hydroxy-9-methoxy-12a-methyl-2,3...)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed